AKAP10 antibody (Internal Region)

Catalog No. ABIN374994

Product Details anti-AKAP10 Antibody

Target: AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))

Binding Specificity: Internal Region

Reactivity: Human, Rat, Mouse, Dog, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This AKAP10 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to AKAP10.

Cross-Reactivity (Details): Species reactivity (expected):Human, Mouse, Canine, Bovine.
Species reactivity (tested):Rat.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-RKVKGKEQEKTSD, from the internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/64000. Western Blot: 0.3-1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for AKAP10

Target: AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))

Alternative Name: AKAP10 (AKAP10 Products)

Synonyms: MGC84612 antibody, AKAP10 antibody, fc10g11 antibody, wu:fc10g11 antibody, si:dkey-197m14.4 antibody, AKAP-10 antibody, D-AKAP-2 antibody, D-AKAP2 antibody, PRKA10 antibody, 1500031L16Rik antibody, B130049N18Rik antibody, D-akap2 antibody, Akap10 antibody, A-kinase anchoring protein 10 antibody, A-kinase anchoring protein 10 L homeolog antibody, A kinase (PRKA) anchor protein 10 antibody, AKAP10 antibody, akap10.L antibody, akap10 antibody, Akap10 antibody

Background: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA, therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS (regulator of G protein signalling) domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction.Synonyms: A kinase anchor protein 10 mitochondrial, D-AKAP-2, Dual specificity A kinase-anchoring protein 2, PRKA10, Protein kinase A-anchoring protein 10

Gene ID: 11216, 9606

UniProt: O43572

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling