The antibody detects: Human MMP-1 Does not cross react to human MMP-2, MMP-3 or MMP-9 To insure lot-to-lot consistency, each batch of product is tested by ELISA to conform with the characteristics of a standard reference reagent.
MMP1
Reactivity: Human
WB, ELISA, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Sample Volume
1 mL
Restrictions
For Research Use only
Format
Liquid
Handling Advice
Protect conjugated products from light. Each reagent is stable for the period shown on the bottle label if stored as directed.
Matrix metalloproteinases (MMPs) are a family of at least 20 structurally related, zinc-containing enzymes that have the ability to brea kDaown connective tissue. MMP-1 is also known as collagenase, fibroblast collagenase, and interstitial collagenase. MMP-1 has shown substrate specificity to collagens I, II, III, VII. VIII and X, aggrecan, versican, tenascin, casein, gelatin, α 1-antitrypsin, myelin basic protein, L-selectin, pro-TNF, IL-1 β, pro-MMP-2 and pro-MMP-9 directly and indirectly by activating other MMPs.