TNF alpha antibody (Biotin)

Catalog No. ABIN375886

This Rat Monoclonal antibody specifically detects TNF alpha in WB, FACS, IHC (p), IHC (fro), ELISA (Detection), ELISPOT (Detection) and MA. It exhibits reactivity toward Mouse.

Quick Overview for TNF alpha antibody (Biotin) (ABIN375886)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This TNF alpha antibody is conjugated to Biotin

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), ELISA (Detection), ELISpot (Detection) (ELISPOT (Detection)), Multiplex Assay (MA)

Clone: MP6-XT3

Product Details anti-TNF alpha Antibody (Biotin)

Purpose: Rat Anti-Mouse TNF-α-BIOT

Specificity: Mouse TNF-α

Characteristics: Biotin Anti-Mouse TNF-alpha antibody for use in flow cytometry, immunohistochemistry, western blotting, ELISA, ELISpot, and multiplex assays.

Immunogen: E. coli-expressed mouse TNF-alpha

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline containing < 0.1 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C

Target Details for TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Alternative Name: TNF-alpha

Background:

Description: Rat Anti-Mouse TNF-α-BIOT

NCBI_Official_Symbol: Tnf

Synoynms: Tumor necrosis factor-α, macrophage cytotoxic factor , MCF, differentiation inducing factor, DIF, cachectin, necrosin, TNFSF-2

Gene ID: 21926

UniProt: P06804

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome