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c-MET antibody (Catalytic Domain)

Name: c-MET antibody (Catalytic Domain)
SKU: ABIN387742
Price: 451 USD
Availability: InStock

MET Reactivity: Human, Mouse WB, IF, IHC (p) Host: Mouse Monoclonal 6AT203 unconjugated

Detection of endogenous Met in HepG2 cell line. (c-MET antibody (Catalytic Domain))

MET/HGFR Antibody (ABIN387742 and ABIN2838000) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjμgation of the secondary antibody and DAB staining. (c-MET antibody (Catalytic Domain))

IHC (p)

2 images

Catalog No. ABIN387742

Datasheet as PDF

Target See all c-MET (MET) Antibodies

c-MET (MET) (Met Proto-Oncogene (MET))
Binding Specificity
41

28

27

24

12

11

9

7

7

7

5

4

4

4

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Catalytic Domain
Reactivity
223

129

97

5

4

4

4

4

2

2

2

1

1

1

1
Human, Mouse
Host
193

38

3

2

2
Mouse
Compatible Secondaries
Clonality
188

50
Monoclonal
Conjugate
126

18

10

10

7

7

7

7

7

7

5

5

2

2

2

2

2

2

2

2

2

2

2
This c-MET antibody is un-conjugated
Application
154

96

39

29

28

20

15

14

13

8

8

5

4

4

1

1

1

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen

This monoclonal antibody is generated from mice immunized with purified recombinant protein encoding the catalytic domain of human Met.

Clone

6AT203

Isotype

IgG1

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MET Reactivity: Human ELISA, FACS, ICC Host: Mouse Monoclonal 5E9B7 unconjugated

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MET Reactivity: Human WB, IF, ICC, IP Host: Rabbit Polyclonal unconjugated

anti-Met Proto-Oncogene (MET) (Internal Region) antibody
MET Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Met Proto-Oncogene (MET) (Tyr1003) antibody
MET Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Met Proto-Oncogene (MET) (AA 83-209) antibody
MET Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Met Proto-Oncogene (MET) (pTyr1234) antibody
MET Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

Application Notes

IF: 1:100. WB: 1:100~500. IHC-P: 1:50~100

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date

6 months
Target

c-MET (MET) (Met Proto-Oncogene (MET))

Alternative Name

MET/HGFR (MET Products)

Background

The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight

155541

Gene ID

4233

NCBI Accession

NP_000236, NP_001120972

UniProt

P08581

Pathways

RTK Signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor