Retinoblastoma 1 antibody (pSer811)

Catalog No. ABIN389648

The Rabbit Polyclonal anti-Retinoblastoma 1 antibody is suitable to detect Retinoblastoma 1 in samples from Human. It has been validated for IF, IHC (p) and DB.

Quick Overview for Retinoblastoma 1 antibody (pSer811) (ABIN389648)

Target: Retinoblastoma 1 (RB1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Retinoblastoma 1 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Dot Blot (DB)

Clone: RB7679

Product Details anti-Retinoblastoma 1 Antibody

Binding Specificity: pSer811

Specificity: This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S811 of human RB.

Predicted Reactivity: Mouse (Murine),Rat (Rattus)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Rb Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S811 of human Rb.

Isotype: Ig Fraction

Application Details

Application Notes: DB = 1:500, IHC (p) = 1:50-100, IF = 1:10-50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Retinoblastoma 1

Target: Retinoblastoma 1 (RB1)

Alternative Name: Rb

Background: Synonyms: Retinoblastoma-associated protein, PP110, P105-RB, RB, RB1,

Molecular Weight: 106159 DA

Gene ID: 5925

UniProt: P06400

Pathways: Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy