TEK antibody (pTyr1113)
Quick Overview for TEK antibody (pTyr1113) (ABIN389946)
Target
See all TEK AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- pTyr1113
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Predicted Reactivity
- B, Zf, M
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This TEK Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1113 of human TEK.
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Isotype
- Ig Fraction
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Application Notes
- DB: 1:500
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Expiry Date
- 6 months
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- TEK (TEK Tyrosine Kinase, Endothelial (TEK))
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Alternative Name
- TEK
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Background
- The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations, the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.
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Molecular Weight
- 125830
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Gene ID
- 83659
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NCBI Accession
- NP_000450
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UniProt
- Q02763
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Pathways
- RTK Signaling, Growth Factor Binding
Target
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