NAGK antibody (N-Acetylglucosamine Kinase) (AA 31-61)

Details for Product anti-NAGK Antibody No. ABIN391111, Supplier: Log in to see
Antigen
  • GNK
  • HSA242910
  • Gnk
  • N-acetyl-l-glutamate kinase
  • N-acetylglucosamine kinase
  • n-acetylglucosamine kinase
  • N-acetylglucosamine kinase L homeolog
  • N-acetyl-l-glutamate kinase
  • NAGK
  • Nagk
  • TTE0216
  • TVG_RS01040
  • PTO_RS00050
  • VF_2145
  • nagK
  • Bm1_35310
  • Deide_2p00250
  • APA01_RS02155
  • Ftrac_3084
  • Pedsa_2544
  • nagk.L
Epitope
AA 31-61, N-Term
24
10
10
10
9
8
2
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine)
93
33
11
1
Host
Rabbit
58
32
3
Clonality (Clone)
Polyclonal ()
Conjugate
This NAGK antibody is un-conjugated
7
7
7
5
5
4
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
79
67
17
17
17
3
3
3
2
1
Options
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Immunogen This NAGK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-61 AA from the N-terminal region of human NAGK.
Clone RB5450
Isotype Ig Fraction
Specificity This NAGK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38~68 amino acids from the N-terminal region of human NAGK.
Predicted Reactivity Cow (Bovine)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Plasmids, Primers & others Plasmids, Primers & others NAGK products on genomics-online (e.g. as negative or positive controls)
Alternative Name NAGK (NAGK Antibody Abstract)
Background N-acetylglucosamine kinase (NAGK) converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. NAGK belongs to the group of N-acetylhexosamine kinases and is a prominent salvage enzyme of amino sugar metabolism in mammals. The predicted 344-amino acid NAGK protein contains the 5 sequence motifs necessary for the binding of ATP by sugar kinases. NAGK shares 91.6% amino acid similarity with mouse Nagk, for which enzyme activity is detectable in all mouse tissues examined, with highest enzymatic activity in testis. It is hypothesized that NAGK has a general role in the catabolic pathways of GlcNAc as well as of ManNAc.
Synonyms: N-acetylglucosamine kinase, GlcNAc kinase
Molecular Weight 37375 DA
Gene ID 55577
NCBI Accession NP_060037
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-N-Acetylglucosamine Kinase (NAGK) (AA 31-61), (N-Term) antibody (ABIN391111) The anti-NAGK Pab (ABIN391111) is used in Western blot to detect NAGK in mouse thymus...
Background publications Hinderlich, Berger, Schwarzkopf, Effertz, Reutter: "Molecular cloning and characterization of murine and human N-acetylglucosamine kinase." in: European journal of biochemistry / FEBS, Vol. 267, Issue 11, pp. 3301-8, 2000 (PubMed).

Lowes, Walker, Alberti, Agius: "Hexokinase isoenzymes in normal and cirrhotic human liver: suppression of glucokinase in cirrhosis." in: Biochimica et biophysica acta, Vol. 1379, Issue 1, pp. 134-42, 1998 (PubMed).

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