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CDK12 antibody (N-Term)

CRKRS Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB3214 unconjugated
Catalog No. ABIN391769
  • Target See all CDK12 (CRKRS) Antibodies
    CDK12 (CRKRS) (Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS))
    Binding Specificity
    • 7
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    Reactivity
    • 31
    • 10
    • 4
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 28
    • 3
    Rabbit
    Clonality
    • 28
    • 3
    Polyclonal
    Conjugate
    • 16
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDK12 antibody is un-conjugated
    Application
    • 17
    • 17
    • 4
    • 2
    • 2
    • 2
    Western Blotting (WB)
    Predicted Reactivity
    Rat
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This CrkRS (CRK7) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CrkRS (CRK7).
    Clone
    RB3214
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CRKRS Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    CDK12 (CRKRS) (Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS))
    Alternative Name
    CrkRS (CRK7) (CRKRS Products)
    Synonyms
    AC017581 antibody, CG7597 antibody, Dmel\\CG7597 antibody, anon-WO0140519.165 antibody, cg7597 antibody, dCDK12 antibody, gi24668141 antibody, CRK7 antibody, CRKR antibody, CRKRS antibody, hCDK12 antibody, 1810022J16Rik antibody, AI646528 antibody, Crk7 antibody, Crkrs antibody, D11Ertd752e antibody, Pksc antibody, Cyclin-dependent kinase 12 antibody, cyclin dependent kinase 12 antibody, cyclin-dependent kinase 12 antibody, Cdk12 antibody, CDK12 antibody
    Background
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
    Molecular Weight
    164155
    Gene ID
    51755
    NCBI Accession
    NP_055898, NP_057591
    UniProt
    Q9NYV4
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