Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Predicted Reactivity
Rat
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This CYP2F1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-424 amino acids from the C-terminal region of human CYP2F1.
C2F1 antibody, CYP2F antibody, MGC68652 antibody, cytochrome P450 family 2 subfamily F member 1 antibody, cytochrome P450 family 2 subfamily F member 1 S homeolog antibody, CYP2F1 antibody, cyp2f1.S antibody, cyp2f1 antibody
Background
CYP2F1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to dehydrogenate 3-methylindole, an endogenous toxin derived from the fermentation of tryptophan, as well as xenobiotic substrates such as naphthalene and ethoxycoumarin.