ELISA: 1/10,000-1/50,000. Western Blot: 1/20,000. Trial Size: ELISA: 1/10,000- 1/15,000. Western Blot: 1/10,000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Buffer
0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Target
ABCB5
(ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 5 (ABCB5))
ABCB5alpha antibody, ABCB5beta antibody, EST422562 antibody, 9230106F14Rik antibody, RGD1566342 antibody, ABCB5 antibody, mdr1 antibody, im:7158730 antibody, wu:fc18f02 antibody, wu:fi81f06 antibody, ATP binding cassette subfamily B member 5 antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 5 antibody, ATP-binding cassette sub-family B member 5 antibody, ABCB5 antibody, Abcb5 antibody, abcb5 antibody, TGME49_249820 antibody, PAAG_04387 antibody, VDBG_00160 antibody, VDBG_02292 antibody
Background
ATP-Binding Cassette proteins comprise a superfamily of transporters with a wide variety of substrates. ABCB5 is a novel member of the human P-glycoprotein family. It functions as a determinant of membrane potential and regulator of cell fusion in physiologic skin progenitor cells. Cell fusion is thought to contribute to tissue differentiation. ABCB5 is predominantly expressed in melanoma cells and is a novel molecular marker for a distinct subset of chemoresistant stem cell phenotype-expressing tumor cells among human epidermal melanocytes. It has been identified as a novel drug transporter in human malignant melanoma. ABCB5 is a rhodamine efflux transporter. This antibody product is intended to be used to confirm cellular localization and expression level of ABCB5.Synonyms: ATP-binding cassette sub-family B member 5