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SYT1 antibody (pSer309)
SYT1
Reactivity: Human, Rat, Mouse
IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SYT1 Antibody
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Target
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SYT1
(Synaptotagmin I (SYT1))
Binding Specificity
All epitopes for SYT1 antibodies
pSer309
Reactivity
All reactivities for SYT1 antibodies
Human, Rat, Mouse
Host
All hosts for SYT1 antibodies
Rabbit
Clonality
All clonalities for SYT1 antibodies
Polyclonal
Conjugate
All conjugates for SYT1 antibodies
This SYT1 antibody is un-conjugated
Application
All applications for SYT1 antibodies
Immunofluorescence (IF)
Specificity
The antibody detects endogenous level of Synaptotagmin only when phosphorylated at Serine 309.
Cross-Reactivity (Details)
Species reactivity (tested):Human, Mouse, Rat.
Purification
Affinity Chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Immunogen
Peptide sequence around phosphorylation site of Serine 309 (G-L-S(p)-D-P) derived from Human.
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
1.0 mg/mL
Buffer
Phosphate Buffered Saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide, 50 % Glycerol
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Target Details for SYT1
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Target
SYT1
(Synaptotagmin I (SYT1))
Alternative Name
Synaptotagmin-1 (SYT1 Products )
Synonyms
P65 antibody, SVP65 antibody, SYT antibody, CG3139 antibody, D. Syt I antibody, DSYT antibody, DSYT2 antibody, DSypt antibody, DSyt antibody, Dmel\\CG3139 antibody, Droso1 antibody, Dsyt2 antibody, SYT I antibody, SYT1 antibody, Syt antibody, Syt 1 antibody, Syt I antibody, Syt-1 antibody, SytI antibody, dSYT antibody, dsyt1 antibody, dsytI antibody, l(2)23AB1 antibody, l(2)23Ba antibody, l(2)k05909 antibody, syt antibody, syt 1 antibody, syt I antibody, syt-1 antibody, syt1 antibody, sytI antibody, AW124717 antibody, G630098F17Rik antibody, Syti antibody, GB20036 antibody, DKFZP459P193 antibody, svp65 antibody, p65 antibody, wu:fj41c01 antibody, wu:fk56d05 antibody, zgc:92899 antibody, synaptotagmin 1 antibody, Synaptotagmin 1 antibody, synaptotagmin I antibody, synaptotagmin-1 antibody, synaptotagmin, p65 antibody, synaptotagmin Ia antibody, synaptotagmin 1 L homeolog antibody, SYT1 antibody, Syt1 antibody, Tsp_06980 antibody, Tsp_08220 antibody, syt1 antibody, LOC100533340 antibody, syt1a antibody, syt1.L antibody
Background
The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse.Synonyms: SVP65, SYT, SYT1, Synaptotagmin I, Synaptotagmin1, SytI, p65
Molecular Weight
approx. 46 kDa
Gene ID
6857
NCBI Accession
NP_001129277
UniProt
P21579
Pathways
Synaptic Vesicle Exocytosis , Dicarboxylic Acid Transport
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