VANGL2 antibody (Internal Region)

Catalog No. ABIN410156

Product Details anti-VANGL2 Antibody

Target: VANGL2 (Vang-Like 2 (VANGL2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VANGL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Specificity: Reacts with VANGL2 protein from human, moise and rat

Purification: Antiserum

Immunogen: Synthetic peptide derived from internal domain of human VANGL2 protein

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for VANGL2

Target: VANGL2 (Vang-Like 2 (VANGL2))

Alternative Name: Vang-Like Protein 2 (VANGL2 Products)

Synonyms: Strabismus antibody, lpp1 antibody, ltap antibody, stb1 antibody, stbm antibody, stbm1 antibody, VANGL2 antibody, LPP1 antibody, LTAP antibody, STB1 antibody, STBM antibody, STBM1 antibody, C530001F03Rik antibody, Lp antibody, Lpp1 antibody, Ltap antibody, Vang1l2 antibody, loop-tail antibody, ska17 antibody, ska antibody, strabismus antibody, tri antibody, vang antibody, vangl2 antibody, vangl2b antibody, vangl2a antibody, VANGL planar cell polarity protein 2 antibody, vang-like 2 (van gogh, Drosophila) antibody, VANGL planar cell polarity protein 2 S homeolog antibody, VANGL planar cell polarity protein 2 L homeolog antibody, vangl2 antibody, VANGL2 antibody, Vangl2 antibody, vangl2.S antibody, vangl2.L antibody

Background: Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process.

Gene ID: 57216

UniProt: Q9ULK5

Pathways: WNT Signaling, Stem Cell Maintenance, Tube Formation, Asymmetric Protein Localization