GZMB antibody (N-Term)
-
- Target See all GZMB Antibodies
- GZMB (Granzyme B (GZMB))
-
Binding Specificity
- N-Term
-
Reactivity
- Human, Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This GZMB antibody is un-conjugated
-
Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificity
- This antibody detects Granzyme B (GZMB) at N-term.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human, mouse
- Purification
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
- Immunogen
- KLH conjugated synthetic peptide selected from the N-terminal region of human GZMB
- Top Product
- Discover our top product GZMB Primary Antibody
-
anti-Granzyme B (GZMB) (AA 21-247) antibody
GZMB Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 73-187) antibodyGZMB Reactivity: Human WB, IHC, StM Host: Mouse Monoclonal GZMB-3014 unconjugated
anti-Granzyme B (GZMB) (AA 21-130) antibodyGZMB Reactivity: Human, Mouse WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Granzyme B (GZMB) antibodyGZMB Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Granzyme B (GZMB) antibodyGZMB Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal CLB-GB11 unconjugated
anti-Granzyme B (GZMB) (AA 175-203), (C-Term) antibodyGZMB Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB19353 unconjugated
anti-Granzyme B (GZMB) (AA 21-247) antibodyGZMB Reactivity: Human WB, IHC, ELISA Host: Mouse Monoclonal 2G12G7 unconjugated
anti-Granzyme B (GZMB) (AA 1-247) antibodyGZMB Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 73-187) antibodyGZMB Reactivity: Human IHC, StM Host: Mouse Monoclonal GZMB-3056 unconjugated
anti-Granzyme B (GZMB) (AA 21-247) antibodyGZMB Reactivity: Human WB, IHC, IF, IHC (p) Host: Mouse Monoclonal 4E4 unconjugated
-
- Application Notes
-
Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
-
- Target
- GZMB (Granzyme B (GZMB))
- Abstract
- GZMB Products
- Synonyms
- CCPI antibody, CGL-1 antibody, CGL1 antibody, CSP-B antibody, CSPB antibody, CTLA1 antibody, CTSGL1 antibody, HLP antibody, SECT antibody, granzyme B antibody, GZMB antibody
- Background
- Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.Synonyms: CGL1, CSPB, CTLA-1, CTLA1, CTSGL1, Cathepsin G-like 1, Cytotoxic T-lymphocyte proteinase 2, Fragmentin-2, GRB, Granzyme-2, Lymphocyte protease, SECT, T-cell serine protease 1-3E
- Molecular Weight
- 27688 Da
- Gene ID
- 3002
- NCBI Accession
- NP_004122
- UniProt
- P10144
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis
-
