KCNJ11 antibody (AA 18-30)
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- Target See all KCNJ11 Antibodies
- KCNJ11 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))
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Binding Specificity
- AA 18-30
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Reactivity
- Human
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This KCNJ11 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Brand
- IHC-plus™
- Specificity
- Human KCNJ11 / Kir6.2. This antibody is expected to recognise isoform 1 (NP_000516.3) only.
- Predicted Reactivity
- Percent identity with other species by BLAST analysis: Human (100%), Gorilla (92%), Monkey (85%), Bovine (85%), Dog (85%), Bat (85%), Horse (85%), Rabbit (85%), Platypus (85%).
- Purification
- Immunoaffinity purified
- Immunogen
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Synthetic peptide C-AEDPAKPRYRARQ from an internal region (near the N-terminus) of human KCNJ11 / Kir6.2 (NP_000516.3). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (92%), Monkey (85%), Bovine (85%), Dog (85%), Bat (85%), Horse (85%), Rabbit (85%), Platypus (85%).
Type of Immunogen: Synthetic peptide - Top Product
- Discover our top product KCNJ11 Primary Antibody
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- Application Notes
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Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:32000), WB (0.1 - 0.3 μg/mL)
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 3.75 μg/mL. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Tris-buffered saline, pH 7.3, 0.5 % BSA, 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Minimize freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze-thaw cycles.
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- Target
- KCNJ11 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))
- Alternative Name
- KCNJ11 / Kir6.2 (KCNJ11 Products)
- Synonyms
- kir6.2 antibody, Kir6.2 antibody, mBIR antibody, BIR antibody, HHF2 antibody, IKATP antibody, KIR6.2 antibody, PHHI antibody, TNDM3 antibody, potassium voltage-gated channel subfamily J member 11 antibody, potassium inwardly-rectifying channel, subfamily J, member 11 antibody, potassium inwardly rectifying channel, subfamily J, member 11 antibody, KCNJ11 antibody, kcnj11 antibody, Kcnj11 antibody
- Background
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Name/Gene ID: KCNJ11
Subfamily: Potassium channel - inward-rectifying
Family: Ion Channel
Synonyms: KCNJ11, BIR, IKATP, HHF2, PHHI, TNDM3, Beta-cell KATP channel, KIR6.2 - Gene ID
- 3767
- NCBI Accession
- NP_000516
- UniProt
- Q14654
- Pathways
- Negative Regulation of Hormone Secretion
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