17 Hydroxyprogesterone (17 OHP) antibody
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- Target
- 17 Hydroxyprogesterone (17 OHP)
- Reactivity
- Please inquire
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Host
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Sheep
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
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Application
- Enzyme Immunoassay (EIA)
- Purification
- Ig Fraction
- Immunogen
- 17-alpha-OH-Progesterone-BTG
- Isotype
- IgG
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- Application Notes
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ELISA: 0.31 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 8.61mg/mL (U.V. abs at 280nm)
- Buffer
- 20 mM Phosphate, 150 mM Sodium Chloride, pH 7.2 containing 0.09 % Sodium Azide as preservative
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- -20 °C
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- Target
- 17 Hydroxyprogesterone (17 OHP)
- Target Type
- Hormone
- Background
- 17-Hydroxyprogesterone (17-OH progesterone or 17OHP) is a C-21 steroid hormone produced during the synthesis of glucocorticoids and sex steroids. It is derived from progesterone via 17-hydroxylase, a P450c17 enzyme, or from 17-hydroxypregnenolone via 3-beta-hydroxysteroid dehydrogenase / Delta 5-4 isomerase. 17-Hydroxyprogesterone is a natural progestogen, and in pregnancy increases in the third trimester primarily due to fetal adrenal production. This hormone is primarily produced in the adrenal glands and to some degree in the gonads, specifically the corpus luteum of the ovary. Hydroxyprogesterone has been used for recurrent miscarriage and various menstrual disorders. Women who have had a spontaneous preterm delivery are at greatly increased risk for preterm delivery in subsequent pregnancies. The results of several small trials have suggested that hydroxyprogesterone may reduce the risk of preterm delivery.Synonyms: 17-Hydroxyprogesterone, 17-alpha-Hydroxy-Progesterone, 17OHP
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