CD81 antibody
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- Target See all CD81 Antibodies
- CD81
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Reactivity
- Human, Rabbit, Cat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD81 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func), Immunocytochemistry (ICC)
- Specificity
- The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.
- Cross-Reactivity (Details)
- Human, Feline (Cat), Rabbit
- Purification
- Purified by protein-A affinity chromatography.
- Purity
- > 95 % (by SDS-PAGE)
- Endotoxin Level
- Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
- Immunogen
- MOLT-4 (human T-ALL cell line)
- Clone
- M38
- Isotype
- IgG1
- Top Product
- Discover our top product CD81 Primary Antibody
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anti-CD81 (CD81) antibody
KO Validated CD81 Reactivity: Human FACS, WB, IF, IHC (p), ICC, BP Host: Rabbit Polyclonal unconjugated
anti-CD81 (CD81) (AA 1-100) antibodyCD81 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-CD81 (CD81) antibodyCD81 Reactivity: Human, Rabbit, Cat FACS, WB, IP, IHC (p), ICC Host: Mouse Monoclonal M38 unconjugated
anti-CD81 (CD81) antibodyCD81 Reactivity: Human FACS, WB, IHC, ELISA Host: Rabbit Monoclonal 9F7 unconjugated Recombinant Antibody
anti-CD81 (CD81) antibody (FITC)CD81 Reactivity: Human, Rabbit, Cat FACS Host: Mouse Monoclonal M38 FITC
anti-CD81 (CD81) (AA 176-203), (C-Term) antibodyCD81 Reactivity: Human, Mouse FACS, WB, IHC (p) Host: Rabbit Polyclonal RB19768 unconjugated
anti-CD81 (CD81) antibody (PE)CD81 Reactivity: Human, Rabbit, Cat FACS Host: Mouse Monoclonal M38 PE
anti-CD81 (CD81) antibodyCD81 Reactivity: Human, Mouse, Rat ELISA, Coat Host: Rabbit Monoclonal C81-2885R unconjugated Recombinant Antibody
anti-CD81 (CD81) antibodyCD81 Reactivity: Human, Mouse, Rat FACS, WB, IHC, IF, Func, StM Host: Mouse Monoclonal 1-3-3-22 unconjugated
anti-CD81 (CD81) antibodyCD81 Reactivity: Human FACS, cELISA Host: Rat Monoclonal QV-6A8-S3 unconjugated
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- Application Notes
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Functional application: In human MOLT-4 T-cell line the antibody M38 inhibits syncytium formation induced by coculture with human T-cell leukemia virus type 1 (HTLV-1)-positive human T-cell lines.
Flow cytometry: recommended dilution: 1 μg/mL.
Western blotting: recommended dilution: 1-2 μg/mL, positive control: Jurkat cells, non-reducing conditions. - Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4
- Preservative
- Azide free
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Do not freeze.
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- Target
- CD81
- Alternative Name
- CD81 (CD81 Products)
- Synonyms
- Tapa-1 antibody, Tapa1 antibody, Tspan28 antibody, CVID6 antibody, S5.7 antibody, TAPA1 antibody, TSPAN28 antibody, CD81 molecule antibody, CD81 molecule b antibody, CD81 antigen antibody, Cd81 molecule antibody, CD81 antibody, cd81b antibody, Cd81 antibody
- Background
- CD81 Molecule,CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.,S5.7, CVID6, TAPA1, TSPAN28
- Gene ID
- 975
- UniProt
- P60033
- Pathways
- Inositol Metabolic Process, Hepatitis C
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