AIF antibody

Catalog No. ABIN4900943

The Mouse Monoclonal anti-AIF antibody is suitable to detect AIF in samples from Human. It has been validated for WB and ELISA.

Quick Overview for AIF antibody (ABIN4900943)

Target: AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AIF antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 8H1-B10-A12

Product Details anti-AIF Antibody

Purpose: Mouse monoclonal to AIF.

Specificity: This antibody detects endogenous levels of AIF and does not cross-react with related proteins.

Characteristics: Mouse Monoclonal to AIF.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Purified recombinant human AIF protein fragments expressed in E.coli.

Isotype: IgG2a

Application Details

Application Notes: WB 1:500-2000
ELISA 1:10000-20000

Comment:

Detected in muscle and skin fibroblasts (at protein level). Isoform 5 is frequently down-regulated in human cancers.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for AIF

Target: AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))

Alternative Name: AIF

Molecular Weight: 67kDa

Gene ID: 9131

UniProt: O95831

Pathways: Apoptosis, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Warburg Effect