DDR1 antibody (AA 602-681)

Catalog No. ABIN4901382

This anti-DDR1 antibody is a Mouse Monoclonal antibody detecting DDR1 in WB and ELISA. Suitable for Human.

Quick Overview for DDR1 antibody (AA 602-681) (ABIN4901382)

Target: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DDR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 2G4E12

Product Details anti-DDR1 Antibody

Binding Specificity: AA 602-681

Purpose: Mouse monoclonal to DDR1.

Specificity: DDR1 Monoclonal Antibody detects endogenous levels of DDR1 protein.

Characteristics: Mouse Monoclonal to DDR1.

Purification: Affinity purification

Immunogen: Purified recombinant fragment of DDR1 (aa602-681) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: WB 1:500-1:2000
ELISA 1:10000

Comment:

Detected in T-47D, MDA-MB-175 and HBL-100 breast carcinoma cells, A-431 epidermoid carcinoma cells, SW48 and SNU-C2B colon carcinoma cells and Hs 294T melanoma cells (at protein level). Expressed at low levels in most adult tissues and is highest in the brain, lung, placenta and kidney. Lower levels of expression are detected in melanocytes, heart, liver, skeletal muscle and pancreas. Abundant in breast carcinoma cell lines. In the colonic mucosa, expressed in epithelia but not in the connective tissue of the lamina propria. In the thyroid gland, expressed in the epithelium of the thyroid follicles. In pancreas, expressed in the islets of Langerhans cells, but not in the surrounding epithelial cells of the exocrine pancreas. In kidney, expressed in the epithelia of the distal tubules. Not expressed in connective tissue, endothelial cells, adipose tissue, muscle cells or cells of hematopoietic origin.

Restrictions: For Research Use only

Handling

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for DDR1

Target: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Alternative Name: DDR1

Gene ID: 780

UniProt: Q08345

Pathways: RTK Signaling, Smooth Muscle Cell Migration