TUBG1 antibody

Catalog No. ABIN5610001

Product Details anti-TUBG1 Antibody

Target: TUBG1 (Tubulin, gamma 1 (TUBG1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TUBG1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Gamma tubulin is a protein encoded by the TUBG1 gene which is approximately 51,1 kDa. Gamma tubulin is localised to the cytoplasm and cytoskeleton. It is involved in the regulation of PLK1 activity at G2/M transition, Sertoli-Sertoli cell junction dynamics and organelle biogenesis and maintenance. This protein falls under the tubulin superfamily. It localizes to the centrosome where it binds to microtubules as part of a complex known as the gamma-tubulin ring complex and is required for microtubule formation and progression of the cell cycle. Gamma tubulin is expressed in the skin, nervous system, lung, kidney and muscle. Mutations in the TUBG1 gene may result in cortical dysplasia. STJ97744 was developed from clone 4A4 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous levels of gamma tubulin.

Specificity: Gamma Tubulin Mouse Monoclonal Antibody (4A4) detects endogenous levels of TUBG1

Characteristics: Mouse Monoclonal to Gamma Tubulin.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogen: synthetic peptide derived from Gamma Tubulin

Clone: 4A4

Isotype: IgG1

Application Details

Application Notes: IHC 1:100-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for TUBG1

Target: TUBG1 (Tubulin, gamma 1 (TUBG1))

Alternative Name: gamma-Tubulin1 (TUBG1) (TUBG1 Products)

Synonyms: GCP-1 antibody, TUBG antibody, TUBGCP1 antibody, TUBC antibody, TUBG3 antibody, gamma-tubulin antibody, Tubg2 antibody, xgam antibody, 1500010O08Rik antibody, AI451582 antibody, AI503389 antibody, Tubg antibody, tubgl antibody, zgc:55894 antibody, tubulin gamma 1 antibody, gamma-tubulin 1 antibody, gamma-tubulin antibody, tubulin gamma 1 L homeolog antibody, Tubulin gamma chain antibody, tubulin, gamma 1 antibody, tubulin gamma-1 chain antibody, TUBG1 antibody, tubg1 antibody, tubg1.L antibody, tbg-1 antibody, Tubg1 antibody, LOC101686824 antibody, LOC101103906 antibody

Gene ID: 7283

UniProt: P23258

Pathways: Microtubule Dynamics, M Phase