JAK1 antibody (AA 960-1040)

Catalog No. ABIN4901822

The Mouse Monoclonal anti-JAK1 antibody has been validated for IHC (p). It is suitable to detect JAK1 in samples from Human, Mouse and Rat.

Quick Overview for JAK1 antibody (AA 960-1040) (ABIN4901822)

Target: JAK1 (Janus Kinase 1 (JAK1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This JAK1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 7G6

Product Details anti-JAK1 Antibody

Binding Specificity: AA 960-1040

Purpose: Mouse monoclonal to JAK1.

Specificity: JAK1 Mouse Monoclonal Antibody (7G6) detects endogenous levels of JAK1

Characteristics: Mouse Monoclonal to JAK1.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogen: synthetic peptide derived from JAK1

Isotype: IgG1

Application Details

Application Notes: IHC 1:100-200

Comment:

Expressed at higher levels in primary colon tumors than in normal colon tissue. The expression level in metastatic colon tumors is comparable to the expression level in normal colon tissue.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for JAK1

Target: JAK1 (Janus Kinase 1 (JAK1))

Alternative Name: JAK1

Gene ID: 3716

UniProt: P23458

Pathways: JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response