JAK1 antibody

Catalog No. ABIN4901825

The Mouse Monoclonal anti-JAK1 antibody has been validated for WB and ELISA. It is suitable to detect JAK1 in samples from Human and Rat.

Quick Overview for JAK1 antibody (ABIN4901825)

Target: JAK1 (Janus Kinase 1 (JAK1))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This JAK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 8B8-E7-G3

Product Details anti-JAK1 Antibody

Purpose: Mouse monoclonal to Jak1.

Specificity: This antibody detects endogenous levels of Jak1 and does not cross-react with related proteins.

Characteristics: Mouse Monoclonal to Jak1.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Purified recombinant human Jak1 protein fragments expressed in E.coli.

Isotype: IgG2a

Application Details

Application Notes: WB 1:500-2000
ELISA 1:10000-20000

Comment:

Expressed at higher levels in primary colon tumors than in normal colon tissue. The expression level in metastatic colon tumors is comparable to the expression level in normal colon tissue.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for JAK1

Target: JAK1 (Janus Kinase 1 (JAK1))

Alternative Name: Jak1

Molecular Weight: 130kDa

Gene ID: 3716

UniProt: P23458

Pathways: JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response