Cadherin 4 antibody

Catalog No. ABIN4903224

Product Details anti-Cadherin 4 Antibody

Target: Cadherin 4 (CDH4)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin 4 antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene.

Purification: Affinity purification

Immunogen: Recombinant protein of human CDH4.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C.

Target Details for Cadherin 4

Target: Cadherin 4 (CDH4)

Alternative Name: CDH4 (CDH4 Products)

Synonyms: cad4 antibody, rcad antibody, R-cadherin antibody, cadherin-4 antibody, AW120700 antibody, R-Cadh antibody, Rcad antibody, Cdh4l antibody, zgc:136316 antibody, CAD4 antibody, RCAD antibody, cadherin 4 antibody, cadherin 4, type 1, R-cadherin (retinal) antibody, Cadherin-4 antibody, cdh4 antibody, Cdh4 antibody, CDH4 antibody, cdh-4 antibody

Gene ID: 1002

UniProt: P55283

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size