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DOCK2 antibody

DOCK2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN4903501
  • Target See all DOCK2 Antibodies
    DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))
    Reactivity
    • 34
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 30
    • 2
    • 2
    Rabbit
    Clonality
    • 32
    • 2
    Polyclonal
    Conjugate
    • 20
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DOCK2 antibody is un-conjugated
    Application
    • 30
    • 13
    • 13
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB)
    Purification
    Affinity purification
    Immunogen
    A synthetic peptide of human DOCK2
    Isotype
    IgG
    Top Product
    Discover our top product DOCK2 Primary Antibody
  • Application Notes
    WB 1:500 - 1:1000
    Comment

    Specifically expressed in hematopoietic cells, Highly expressed in peripheral blood leukocytes, and expressed at intermediate level in thymus and spleen, Expressed at very low level in the small intestine and colon

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20C. Avoid freeze / thaw cycles.
  • Target
    DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))
    Alternative Name
    DOCK2 (DOCK2 Products)
    Synonyms
    AI662014 antibody, AW122239 antibody, CED-5 antibody, Hch antibody, MBC antibody, dedicator of cytokinesis 2 antibody, dedicator of cyto-kinesis 2 antibody, DOCK2 antibody, dock2 antibody, Dock2 antibody
    Background
    The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP.
    Molecular Weight
    211.948 kDa
    Gene ID
    1794
    UniProt
    Q92608
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