ATR
Reactivity: Human
ELISA, IHC
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50 % glycerol, 0.02 % sodium azide)
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Aliquot to avoid repeated freezing and thawing.
Shechter, Costanzo, Gautier: "Regulation of DNA replication by ATR: signaling in response to DNA intermediates." in: DNA repair, Vol. 3, Issue 8-9, pp. 901-8, (2004) (PubMed).
Zhou, Lu, Wulf, Lu: "Phosphorylation-dependent prolyl isomerization: a novel signaling regulatory mechanism." in: Cellular and molecular life sciences : CMLS, Vol. 56, Issue 9-10, pp. 788-806, (2001) (PubMed).
Kastan, Lim: "The many substrates and functions of ATM." in: Nature reviews. Molecular cell biology, Vol. 1, Issue 3, pp. 179-86, (2001) (PubMed).