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PI3 antibody

PI3 Reactivity: Human WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN4950906
  • Target See all PI3 Antibodies
    PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))
    Reactivity
    • 48
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 35
    • 11
    • 1
    • 1
    Rabbit
    Clonality
    • 37
    • 11
    Polyclonal
    Conjugate
    • 26
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PI3 antibody is un-conjugated
    Application
    • 40
    • 15
    • 13
    • 13
    • 10
    • 9
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Antigen affinity
    Immunogen
    Amino acids A61-Q117 from the human protein were used as the immunogen for the Elafin antibody.
    Isotype
    IgG
    Top Product
    Discover our top product PI3 Primary Antibody
  • Application Notes
    Optimal dilution of the Elafin antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (FFPE): 0.5-1 μg/mL,ELISA: 0.1-0.5 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    After reconstitution, the Elafin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))
    Alternative Name
    Elafin (PI3 Products)
    Synonyms
    ESI antibody, SKALP antibody, WAP3 antibody, WFDC14 antibody, cementoin antibody, trappin-2 antibody, TRAPPIN-2 antibody, elafin antibody, peptidase inhibitor 3 antibody, peptidase inhibitor 3, skin-derived (SKALP) antibody, PI3 antibody
    Background
    Elafin, also known as peptidase inhibitor 3 or skin-derived antileukoprotease (SKALP), is a protein that in humans is encoded by the PI3 gene. This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. And this gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.
    UniProt
    P19957
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