KAT2A antibody

Catalog No. ABIN4951155

Product Details anti-KAT2A Antibody

Target: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KAT2A antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogen: Amino acids DPARPGLSQQQRASQRKAQVRGLPRAKKLEKL of human KAT2A/GCN5 were used as the immunogen for the GCN5 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the GCN5 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the GCN5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for KAT2A

Target: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Alternative Name: GCN5 / KAT2A (KAT2A Products)

Synonyms: KAT2A antibody, GCN5L2 antibody, GCN5 antibody, PCAF-b antibody, hGCN5 antibody, 1110051E14Rik antibody, AW212720 antibody, Gcn5 antibody, Gcn5l2 antibody, mmGCN5 antibody, K(lysine) acetyltransferase 2A antibody, lysine acetyltransferase 2A antibody, histone acetyltransferase KAT2A antibody, ras-related protein Rab-5C antibody, KAT2A antibody, LOC100176452 antibody, LOC100597293 antibody, Kat2a antibody

Background: Histone acetyltransferase KAT2A, also called GCN5 and GCN5L2, is an enzyme that in humans is encoded by the KAT2A gene. It is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. The GCN5 protein, a regulator of transcription activation in yeast, promotes maximal levels of transcription by 2 transcriptional activators, GCN4 and the HAP2-HAP3-HAP4 complex. The GCN4 protein activates transcription of a large number of amino acid biosynthetic genes under limiting amino acid conditions and the HAP2-HAP3-HAP4 complex is thought to mediate transcription of genes involved in respiratory functions. GCN5 also functions as a repressor of NF-kappa-B by promoting ubiquitination of the NF-kappa-B subunit RELA in a HAT-independent manner.

UniProt: Q92830

Pathways: Chromatin Binding, Tube Formation