Lipocalin 2 antibody (AA 21-198)

Catalog No. ABIN4951598

Product Details anti-Lipocalin 2 Antibody

Target: Lipocalin 2 (LCN2)

Binding Specificity: AA 21-198

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lipocalin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Purification: Antigen affinity

Immunogen: Amino acids 21-198 of rat Lipocalin 2 were used as the immunogen for the LCN2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the LCN2 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the LCN2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for Lipocalin 2

Target: Lipocalin 2 (LCN2)

Alternative Name: Lipocalin 2 / NGAL / LCN2 (LCN2 Products)

Synonyms: LCN2 antibody, 24p3 antibody, MSFI antibody, NGAL antibody, AW212229 antibody, Sip24 antibody, lipocalin 2 antibody, LCN2 antibody, Lcn2 antibody

Background: Europhile gelatinase-associated lipocalin (NGAL) is a protein that in humans is encoded by the LCN2 gene. The binding of lipocalin-2 to bacterial siderophores is important in the innate immune response to bacterial infection. Upon encountering invading bacteria the toll-like receptors on immune cells stimulate the synthesis and secretion of lipocalin-2. Secreted lipocalin-2 then limits bacterial growth by sequestering iron-containing siderophores. Lipocalin-2 also functions as a growth factor.

UniProt: P30152

Pathways: Cellular Response to Molecule of Bacterial Origin, Transition Metal Ion Homeostasis