MGP antibody

Catalog No. ABIN4951722

Product Details anti-MGP Antibody

Target: MGP (Matrix Gla Protein (MGP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MGP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogen: Amino acids Y20-F96 from the human protein were used as the immunogen for the MGP antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MGP antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (FFPE): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the MGP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for MGP

Target: MGP (Matrix Gla Protein (MGP))

Alternative Name: MGP / Matrix Gla protein (MGP Products)

Synonyms: MGLAP antibody, NTI antibody, Mglap antibody, mgp-A antibody, MGP antibody, LOC100136434 antibody, mgp antibody, matrix Gla protein antibody, matrix Gla protein L homeolog antibody, MGP antibody, Mgp antibody, mgp.L antibody, mgp antibody

Background: Matrix Gla protein (MGP) is an 84-residue vitamin K-dependent protein initially isolated from bovine bone. In addition, MGP is a 10-kD protein produced and secreted by vascular smooth muscle cells and chondrocytes and significantly accumulated in bone, cartilage, and dentin. It is also expressed at high levels in heart, kidney, and lung and is upregulated by vitamin D in bone cells. MGP has a high affinity binding to calcium ions, similar to other Gla-containing proteins. The protein acts as an inhibitor of vascular mineralization and plays a role in bone organization. And this gene is mapped to 12p12.3.

UniProt: P08493