FAK antibody

Catalog No. ABIN4953249

This Mouse Monoclonal antibody specifically detects FAK in WB, IF, IP and ICC. It exhibits reactivity toward Human and Primate.

Quick Overview for FAK antibody (ABIN4953249)

Target: FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

Reactivity: Human, Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This FAK antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: 3D8-H11-E12

Product Details anti-FAK Antibody

Purification: Protein G affinity

Immunogen: A human recombinant partial protein was used as the immunogen for this FAK antibody.

Isotype: IgG1

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the FAK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,ICC/IF: 1:200,Immunoprecipitation: suitable

Restrictions: For Research Use only

Handling

Buffer: Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300

Storage: -20 °C

Storage Comment: Store the FAK antibody at -20°C.

Target Details for FAK

Target: FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

Alternative Name: FAK / Focal Adhesion Kinase

Background: Focal Adhesion Kinase, or FAK, is a non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. [UniProt]

UniProt: Q05397

Pathways: Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling