E-cadherin antibody (AA 833-862)

Catalog No. ABIN3030244

This Rabbit Polyclonal antibody specifically detects E-cadherin in WB, FACS and ELISA. It exhibits reactivity toward Human.

Quick Overview for E-cadherin antibody (AA 833-862) (ABIN3030244)

Target: E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This E-cadherin antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Product Details anti-E-cadherin Antibody

Binding Specificity: AA 833-862

Purification: Purified

Immunogen: A portion of amino acids 833-862 from the human protein was used as the immunogen for this anti-E Cadherin antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the anti-E Cadherin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the anti-E Cadherin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for E-cadherin

Target: E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))

Alternative Name: E Cadherin

Background: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. E Cadherin is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. [UniProt]

UniProt: P12830

Pathways: WNT Signaling, Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation