Insulin Receptor antibody (AA 546-574)

Catalog No. ABIN3028738

This Rabbit Polyclonal antibody specifically detects Insulin Receptor in WB and ELISA. It exhibits reactivity toward Mouse.

Quick Overview for Insulin Receptor antibody (AA 546-574) (ABIN3028738)

Target: Insulin Receptor (INSR)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Insulin Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Insulin Receptor Antibody

Binding Specificity: AA 546-574

Cross-Reactivity (Details): Expected species reactivity: Rat

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 546-574 from the mouse protein was used as the immunogen for this anti-Insulin Receptor antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the anti-Insulin Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the anti-Insulin Receptor antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Insulin Receptor

Target: Insulin Receptor (INSR)

Alternative Name: Insulin Receptor

Background: This receptor binds insulin and has a tyrosine-protein kinase activity. When present in a hybrid receptor with IGF1R, binds IGF1.

UniProt: P15208

Pathways: NF-kappaB Signaling, RTK Signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity