Aurora A antibody (AA 93-120)

Catalog No. ABIN3030070

This Rabbit Polyclonal antibody specifically detects Aurora A in WB and ELISA. It exhibits reactivity toward Mouse.

Quick Overview for Aurora A antibody (AA 93-120) (ABIN3030070)

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aurora A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Aurora A Antibody

Binding Specificity: AA 93-120

Purpose: Aurka Antibody

Purification: Antigen affinity

Immunogen: A portion of amino acids 93-120 from the mouse protein was used as the immunogen for this Aurka antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Aurka antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Aurka antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Aurora A

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Alternative Name: Aurka

Background: Contributes to the regulation of cell cycle progression. Required for normal mitosis. Associates with the centrosome and the spindle microtubules during mitosis and functions in centrosome maturation, spindle assembly, maintenance of spindle bipolarity, centrosome separation and mitotic checkpoint control. Phosphorylates numerous target proteins, including ARHGEF2, BRCA1, KIF2A, NDEL1, PARD3, PLK1 and BORA. Regulates KIF2A tubulin depolymerase activity (By similarity). Required for normal axon formation. Plays a role in microtubule remodeling during neurite extension. Important for microtubule formation and/or stabilization.

UniProt: P97477

Pathways: Cell Division Cycle, Asymmetric Protein Localization