ERBB4 antibody (AA 1141-1166)

Catalog No. ABIN3029485

Product Details anti-ERBB4 Antibody

Target: ERBB4 (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4))

Binding Specificity: AA 1141-1166

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERBB4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity (Details): Expected species reactivity: Rat

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 1141-1166 from the human protein was used as the immunogen for this ERBB4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the ERBB4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ERBB4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for ERBB4

Target: ERBB4 (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4))

Alternative Name: ERBB4 (ERBB4 Products)

Synonyms: erbb4 antibody, si:ch211-227n20.1 antibody, Her4 antibody, c-erbB-4 antibody, HER4 antibody, p180erbB4 antibody, erb-b2 receptor tyrosine kinase 4 antibody, erb-b2 receptor tyrosine kinase 4a antibody, v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) antibody, erb-b2 receptor tyrosine kinase 4 L homeolog antibody, receptor tyrosine-protein kinase ErbB-4 antibody, ERBB4 antibody, erbb4a antibody, erbb4 antibody, erbb4.L antibody, Tsp_13582 antibody, Erbb4 antibody

Background: ERBB4 acts as cell-surface receptor for the neuregulins NRG1, NRG2, NRG3 and NRG4 and the EGF family members BTC, EREG and HBEGF. Ligand binding triggers receptor dimerization and autophosphorylation at specific tyrosine residues that then serve as binding sites for scaffold proteins and effectors. [UniProt]

UniProt: Q15303

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway