LRRK2 antibody (C-Term)

Catalog No. ABIN3031611

The Mouse Monoclonal anti-LRRK2 antibody (Clone 133AT720) (ABIN3031611) specifically detects LRRK2 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for LRRK2 antibody (C-Term) (ABIN3031611)

Target: LRRK2 (Leucine-Rich Repeat Kinase 2 (LRRK2))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This LRRK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 133AT720

Product Details anti-LRRK2 Antibody

Binding Specificity: C-Term

Purpose: LRRK2 Antibody

Purification: Purified

Immunogen: This LRRK2 antibody was raised in mice using purified His-tagged recombinant protein comprised of the C-terminal 261 residues of LRRK2.

Isotype: IgG1

Application Details

Application Notes: Titration of the LRRK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the LRRK2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for LRRK2

Target: LRRK2 (Leucine-Rich Repeat Kinase 2 (LRRK2))

Alternative Name: LRRK2

Background: This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.

UniProt: Q5S007

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development