BAD antibody (pSer96)

Catalog No. ABIN3028494

This anti-BAD antibody is a Rabbit Polyclonal antibody detecting BAD in ELISA and DB. Suitable for Mouse.

Quick Overview for BAD antibody (pSer96) (ABIN3028494)

Target: BAD (BCL2-Associated Agonist of Cell Death (BAD))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAD antibody is un-conjugated

Application: ELISA, Dot Blot (DB)

Product Details anti-BAD Antibody

Binding Specificity: pSer96

Purification: Antigen affinity purified

Immunogen: This phospho-BAD antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS96 of mouse BAD.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the phospho-BAD antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the phospho-BAD antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for BAD

Target: BAD (BCL2-Associated Agonist of Cell Death (BAD))

Alternative Name: Bad

Background: BAD promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.

UniProt: Q61337

Pathways: MAPK Signaling, PI3K-Akt Signaling, RTK Signaling, Apoptosis, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events