BAD antibody (AA 69-168)

Catalog No. ABIN560023

This Mouse Monoclonal antibody specifically detects BAD in WB, ELISA and PLA. It exhibits reactivity toward Human. It has been mentioned in 2+ publications

Quick Overview for BAD antibody (AA 69-168) (ABIN560023)

Target: BAD (BCL2-Associated Agonist of Cell Death (BAD))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BAD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Proximity Ligation Assay (PLA)

Clone: 3H8

Product Details anti-BAD Antibody

Binding Specificity: AA 69-168

Purpose: Mouse monoclonal antibody raised against a partial recombinant BAD.

Sequence: IRSRHSSYPA GTEDDEGMGE EPSPFRGRSR SAPPNLWAAQ RYGRELRRMS DEFVDSFKKG LPRPKSAGTA TQMRQSSSWT RVFQSWWDRN LGRGSSAPSQ

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: BAD (AAH01901, 69 a.a. ~ 168 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-BAD antibody (ABIN560023)

Liu, Chen, Chau, Jan, Chen, Hsu, Lin, Juang, Lu, Cheng, Chen, Chang, Ting, Kao, Hsiao, Huang: "Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 5, pp. 1335-49, (2013) (PubMed).

Gan, Chen, Zhong, Wang, Lam, Liu, Zhang, Zhou, Yu, Si, Wang, Jin: "ZIC1 is downregulated through promoter hypermethylation, and functions as a tumor suppressor gene in colorectal cancer." in: PLoS ONE, Vol. 6, Issue 2, pp. e16916, (2011) (PubMed).

Target Details for BAD

Target: BAD (BCL2-Associated Agonist of Cell Death (BAD))

Alternative Name: BAD

Background: Full Gene Name: BCL2-associated agonist of cell death
Synonyms: BBC2,BCL2L8

Gene ID: 572

Pathways: MAPK Signaling, PI3K-Akt Signaling, RTK Signaling, Apoptosis, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events