ERBB4 antibody (pTyr1188)

Catalog No. ABIN3029488

This Rabbit Polyclonal antibody specifically detects ERBB4 in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for ERBB4 antibody (pTyr1188) (ABIN3029488)

Target: ERBB4 (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERBB4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-ERBB4 Antibody

Binding Specificity: pTyr1188

Purpose: Phospho-HER4/ERBB4 Antibody (pY1188)

Purification: Antigen affinity

Immunogen: This phospho-HER4 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY1188 of human HER4.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the phospho-HER4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot the phospho-HER4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for ERBB4

Target: ERBB4 (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4))

Alternative Name: HER4/ERBB4

Background: The HER4/ERBB4 gene is a member of the type I receptor tyrosine kinase subfamily that includes EGFR, ERBB2, and ERBB3. It encodes a receptor for NDF/heregulin.

UniProt: Q15303

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway