c-MET antibody (pTyr1356)

Catalog No. ABIN3028834

This Rabbit Polyclonal antibody specifically detects c-MET in ELISA and DB. It exhibits reactivity toward Human.

Quick Overview for c-MET antibody (pTyr1356) (ABIN3028834)

Target: c-MET (MET) (Met Proto-Oncogene (MET))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This c-MET antibody is un-conjugated

Application: ELISA, Dot Blot (DB)

Product Details anti-c-MET Antibody

Binding Specificity: pTyr1356

Purification: Antigen affinity purified

Immunogen: This phospho-MET antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY1356 of human MET.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the phospho-MET antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the phospho-MET antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for c-MET

Target: c-MET (MET) (Met Proto-Oncogene (MET))

Alternative Name: MET

Background: The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma.

UniProt: P08581

Pathways: RTK Signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor