Tuberin antibody (pSer1096)
Quick Overview for Tuberin antibody (pSer1096) (ABIN3029317)
Target
See all Tuberin (TSC2) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pSer1096
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Purpose
- Phospho-TSC2 Antibody (pS1096)
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Purification
- Antigen affinity
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Immunogen
- This phospho-TSC2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS1096 of human TSC2.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the phospho-TSC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the phospho-TSC2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
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Alternative Name
- TSC2
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Background
- Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.
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UniProt
- P49815
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Pathways
- RTK Signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
Target
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