Nuclear Coactivator Protein (p100) (C-Term) antibody
Reactivity: Human
WB, IHC
Host: Guinea Pig
Polyclonal
unconjugated
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- Target
- Nuclear Coactivator Protein (p100)
- Binding Specificity
- C-Term
- Reactivity
- Human
- Host
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Guinea Pig
- Clonality
- Polyclonal
- Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Cross-Reactivity
- Cow (Bovine), Fruit Fly (Drosophila melanogaster), Human, Rat (Rattus), Mouse (Murine)
- Immunogen
- synthetic duplicated C-terminus of human p100 protein
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- Application Notes
- Dilution for IHC: 1:100 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- serum
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
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- Target
- Nuclear Coactivator Protein (p100)
- Alternative Name
- p100 nuclear coactivator protein
- Background
- P100 is a ubiquitously expressed protein highly conserved during evolution, enhancing e.g. transciptional activity of EBNA2 of EBV, bridging STAT6 with the basal transcription machinery, also described as a part of the RNA polymerase II holoenzyme. The antiserum localized p100 also in the ER and lipid droplets of milk secreting cells. In addition to the nuclear localization the protein was also detected in cytosolic fractions from lactating mammary gland, in storage lipid droplets from adipocytes and in ER from liver.
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