Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Serotonin Receptor 4 antibody

HTR4 Reactivity: Human, Rat, Mouse WB, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN498370
  • Target See all Serotonin Receptor 4 (HTR4) Antibodies
    Serotonin Receptor 4 (HTR4)
    Reactivity
    • 62
    • 34
    • 33
    • 11
    • 10
    • 9
    • 7
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    Human, Rat, Mouse
    Host
    • 76
    • 1
    Rabbit
    Clonality
    • 76
    • 1
    Polyclonal
    Conjugate
    • 30
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This Serotonin Receptor 4 antibody is un-conjugated
    Application
    • 61
    • 27
    • 26
    • 26
    • 13
    • 9
    • 7
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody detects endogenous levels of SR-4 protein. (region surrounding Asp47)
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product HTR4 Primary Antibody
  • Application Notes
    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 15 mM Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Serotonin Receptor 4 (HTR4)
    Alternative Name
    Serotonin Receptor 4 / HTR4 (HTR4 Products)
    Synonyms
    5-HT4 antibody, 5-HT<4L> antibody, 5HTR4 antibody, 5-HT4S antibody, 5-HT4R antibody, 5 hydroxytryptamine (serotonin) receptor 4 antibody, 5-hydroxytryptamine receptor 4 antibody, Htr4 antibody, HTR4 antibody
    Background
    Serotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it is predominantly expressed in the gut, platelets and central nervous system (CNS). In the CNS, serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors. SR-3 is a ligand-gated ion channel, whereas all other known serotonin receptor subtypes are G protein-coupled receptors. The gene which encodes SR-3 maps to human chromosome 11q23.1-q23.2. SR-4 mediates widespread effects in central and peripheral nervous systems. The gene which encodes SR-4 maps to human chromosome 5q31-q33. SR-7 belongs to the superfamily of G protein-coupled receptors. The gene which encodes SR-7 maps to human chromosome 10q21-q24.Synonyms: 5-HT-4, 5-HT4, 5-hydroxytryptamine receptor 4
    Molecular Weight
    approx. 48 kDa
    Gene ID
    3360
    NCBI Accession
    NP_000861
    UniProt
    Q13639
    Pathways
    JAK-STAT Signaling, cAMP Metabolic Process, S100 Proteins
You are here:
Support