PITX1 antibody

Catalog No. ABIN498429

Product Details anti-PITX1 Antibody

Target: PITX1 (Paired-Like Homeodomain 1 (PITX1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PITX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects endogenous levels of Pitx1 protein. (region surrounding Glu130)

Cross-Reactivity (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Purity: > 95 % by SDS-PAGE

Application Details

Application Notes: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PITX1

Target: PITX1 (Paired-Like Homeodomain 1 (PITX1))

Alternative Name: PITX1 (PITX1 Products)

Synonyms: PITX1 antibody, bft antibody, potx antibody, ptx1 antibody, xPitx1 antibody, MGC79589 antibody, X-PITX-1 antibody, BFT antibody, CCF antibody, LBNBG antibody, POTX antibody, PTX1 antibody, Bft antibody, zgc:136976 antibody, P-OTX antibody, Potx antibody, Ptx1 antibody, paired like homeodomain 1 antibody, paired like homeodomain 2 antibody, paired-like homeodomain 1 antibody, paired-like homeodomain transcription factor 1 antibody, Pitx1 protein antibody, PITX1 antibody, pitx1 antibody, PITX2 antibody, Pitx1 antibody

Background: Pitx1 and Pitx2 are highly homologous, bicoid-related transcription factors. Pitx1 is a bicoid-related homeodomain factor that exhibits preferential expression in the hindlimb, as well as expression in the developing anterior pituitary gland and first branchial arch. Deletion of the Pitx1 locus results in decreased distal expression of the hindlimb-specific marker, the T-box factor (Tbx4). Pitx1 may modulate morphogenesis, growth and patterning of a specific hindlimb region, and serves as a component of the variables that influence morphological and growth distinctions in forelimb and hindlimb identity.Synonyms: BFT, Hindlimb-expressed homeobox protein backfoot, Homeobox protein PITX1, PTX1, Paired-like homeodomain transcription factor 1, Pituitary homeobox 1

Molecular Weight: approx. 34 kDa

Gene ID: 5307

NCBI Accession: NP_002644

UniProt: P78337