S100A10 antibody

Catalog No. ABIN498500

Product Details anti-S100A10 Antibody

Target: S100A10 (S100 Calcium Binding Protein A10 (S100A10))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This S100A10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects endogenous levels of S-100A10 protein. (region surrounding Val52)

Cross-Reactivity (Details): Species reactivity (expected):Mouse and RatSpecies reactivity (tested):Human.

Purification: Affinity chromatography

Purity: > 95 % by SDS-PAGE

Application Details

Application Notes: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: PBS, pH 7.2, 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for S100A10

Target: S100A10 (S100 Calcium Binding Protein A10 (S100A10))

Alternative Name: S100A10 (S100A10 Products)

Synonyms: 42C antibody, ANX2L antibody, ANX2LG antibody, CAL1L antibody, CLP11 antibody, Ca[1] antibody, GP11 antibody, P11 antibody, p10 antibody, AA409961 antibody, AL024248 antibody, CAL12 antibody, Cal1l antibody, p11 antibody, s100a10 antibody, 42c antibody, anx2l antibody, anx2lg antibody, cal1l antibody, calpactin antibody, clp11 antibody, gp11 antibody, p11-A antibody, s100a10b antibody, hm:zehn1116 antibody, wu:fa94d11 antibody, wu:fb05h04 antibody, zgc:56142 antibody, zgc:101880 antibody, S100 calcium binding protein A10 antibody, S100 calcium binding protein A10 (calpactin) antibody, S100 calcium binding protein A10 L homeolog antibody, S100 calcium binding protein A10b antibody, S100 calcium binding protein A10a antibody, S100A10 antibody, S100a10 antibody, s100a10 antibody, s100a10.L antibody, s100a10b antibody, s100a10a antibody

Background: The S-100 family of calcium-activated proteins interact with a range of target proteins to modulate biological signaling pathways. Numerous cancer cell lines overexpress the plasminogen receptor S-100A10 on the extracellular cell surface, where it forms a heterotetrameric complex with Annexin II, though this association is not required for plasma membrane localization or binding and activation of plasminogen. Additionally, S-100A10 acts as a cellular chaperone for hepatitis B (Hep B) virus polymerase. Hep B virus polymerase normally localizes to the cytoplasm only, though in the presence of S-100A10 a portion relocates to the nucleus, implying a role for S-100A10 and intracellular calcium in the process of viral replication.Synonyms: ANX2LG, CAL1L, CLP11, Calpactin-1 light chain, Cellular ligand of annexin II, S100 calcium-binding protein A10, S100-A10

Molecular Weight: approx. 11 kDa

Gene ID: 6281

NCBI Accession: NP_002957

UniProt: P60903

Pathways: S100 Proteins