Desmoglein 2 antibody
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- Target See all Desmoglein 2 (DSG2) Antibodies
- Desmoglein 2 (DSG2)
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Desmoglein 2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- This antibody detects endogenous levels of Dsg2 protein. (region surrounding Val440)
- Cross-Reactivity (Details)
- Species reactivity (tested):Human.
- Purification
- Affinity chromatography
- Purity
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product DSG2 Primary Antibody
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- Application Notes
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Desmoglein 2 (DSG2)
- Alternative Name
- Desmoglein-2 (DSG2 Products)
- Synonyms
- DSG2 antibody, dsc antibody, dsga antibody, si:dkeyp-51f12.6 antibody, wu:fj23f02 antibody, ARVC10 antibody, ARVD10 antibody, CDHF5 antibody, CMD1BB antibody, HDGC antibody, AA408168 antibody, D18Ertd293e antibody, desmoglein 2 antibody, desmoglein 2, tandem duplicate 1 antibody, DSG2 antibody, dsg2.1 antibody, dsg2 antibody, Dsg2 antibody
- Background
- Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 2 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.Synonyms: CDHF5, Cadherin family member 5, DSG2, HDGC
- Molecular Weight
- approx. 140 kDa
- Gene ID
- 1829
- NCBI Accession
- NP_001934
- UniProt
- Q14126
- Pathways
- Cell-Cell Junction Organization
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