GP6 antibody (AA 121-220) (Alexa Fluor 750)

Catalog No. ABIN5003665

Product Details anti-GP6 Antibody (Alexa Fluor 750)

Target: GP6 (Glycoprotein VI (Platelet) (GP6))

Binding Specificity: AA 121-220

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GP6 antibody is conjugated to Alexa Fluor 750

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GPVI/Glycoprotein VI

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GP6

Target: GP6 (Glycoprotein VI (Platelet) (GP6))

Alternative Name: Glycoprotein VI (GP6 Products)

Synonyms: BDPLT11 antibody, GPIV antibody, GPVI antibody, 9830166G18Rik antibody, Gm469 antibody, Gpvi antibody, GP6 antibody, glycoprotein VI platelet antibody, glycoprotein 6 (platelet) antibody, glycoprotein VI antibody, platelet glycoprotein VI antibody, GP6 antibody, Gp6 antibody, LOC103346235 antibody

Background:

Synonyms: Glycoprotein VI, GP6, GPIV, GPVI, MGC138168, Platelet collagen receptor, Platelet glycoprotein VI, Platelet glycoprotein VI precursor, GPVI_HUMAN.

Background: Glycoprotein VI (GPVI) is a membrane glycoprotein receptor for collagen found in platelets. GPVI plays an important role in platelet procoagulant activity which may contribute to arterial and venous thrombus formation. GPVI is expressed in megakaryocytes and platelets. Patients deficient in GPVI suffer from mild hemorrhagic diathesis and their platelets fail to aggregate in response to collagen. There are three isoforms.

Gene ID: 51206

UniProt: Q9HCN6