IL-1 beta antibody (AA 161-269) (AbBy Fluor® 680)

Catalog No. ABIN5005253

The AbBy Fluor® 680-conjugated Rabbit Polyclonal anti-IL-1 beta antibody (ABIN5005253) specifically detects IL-1 beta in WB. The antibody is reactive with Human samples.

Quick Overview for IL-1 beta antibody (AA 161-269) (AbBy Fluor® 680) (ABIN5005253)

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-1 beta antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB)

Product Details anti-IL-1 beta Antibody (AbBy Fluor® 680)

Binding Specificity: AA 161-269

Purpose: IL-1 Beta Polyclonal Antibody, AbBy Fluor-680 Conjugated

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Bee

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IL-1 Beta

Isotype: IgG

Application Details

Application Notes: WB(1:500-2000)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for IL-1 beta

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Alternative Name: IL-1 Beta

Background:

Synonyms: IL-1, IL1F2, IL1-BETA, Interleukin-1 beta, IL-1 beta, Catabolin, IL1B

Background: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.

Gene ID: 3553

UniProt: P01584

Pathways: NF-kappaB Signaling, Interferon-gamma Pathway, TLR Signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome