Napsin (AA 150-350) antibody
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- Target
- Napsin
- Binding Specificity
- AA 150-350
- Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- Un-conjugated
- Application
- Immunohistochemistry (IHC), Western Blotting (WB)
- Purification
- Protein G Chromatography
- Immunogen
- A partial length recombinant Napsin protein (amino acids 150-350) was used as the immunogen for this antibody
- Clone
- ABM4H60
- Isotype
- IgG1 kappa
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- Application Notes
- WB: 0.5-1 μg/mL, IHC: 5-10 μg/mL
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- PBS containing 0.05 % BSA, PH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Target
- Napsin
- Background
- Napsin A, a human aspartic proteinase is found primarily in type II pneumocytes and alveolar macrophages and predominantly expressed in lung and kidney. It is a reliable marker for pulmonary adenocarcinoma and is expressed in a subset of ovarian clear cell carcinomas (O-CCCs), endometrial (EM) CCCs, and endometrioid carcinomas (EC). It is also useful in evaluating SH (Sclerosing hemangiomas) (23194051). Napsin A acts as an anti-apoptotic protein that promotes resistance to cisplatin by degradation of the tumor suppressor p53, which is regulator of the cell cycle and co-works with cyclin kinase inhibitors as p21 and p27.
- Molecular Weight
- 44 kDa
- Gene ID
- 9476
- UniProt
- O96009
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