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S1PR1 antibody (AA 1-320)
S1PR1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-S1PR1 Antibody
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Target
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S1PR1
(Sphingosine-1-Phosphate Receptor 1 (S1PR1))
Binding Specificity
All epitopes for S1PR1 antibodies
AA 1-320
Reactivity
All reactivities for S1PR1 antibodies
Human
Host
All hosts for S1PR1 antibodies
Rabbit
Clonality
All clonalities for S1PR1 antibodies
Polyclonal
Conjugate
All conjugates for S1PR1 antibodies
This S1PR1 antibody is un-conjugated
Application
All applications for S1PR1 antibodies
Western Blotting (WB)
Purification
Protein A Chromatography
Immunogen
A partial length recombinant S1PR1 protein (amino acids 1-320) was used as the immunogen for this antibody.
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB:4-6 μg/mL
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Target Details for S1PR1
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Target
S1PR1
(Sphingosine-1-Phosphate Receptor 1 (S1PR1))
Alternative Name
S1PR1 (S1PR1 Products )
Synonyms
CD363 antibody, CHEDG1 antibody, D1S3362 antibody, ECGF1 antibody, EDG-1 antibody, EDG1 antibody, S1P1 antibody, AI849002 antibody, Edg1 antibody, Lpb1 antibody, S1p antibody, S1p1 antibody, S1P receptor 1 antibody, S1P receptor Edg-1 antibody, edg1 antibody, etID43307.22 antibody, s1p1 antibody, wu:fb98f05 antibody, s1pr1 antibody, xts1p1 antibody, sphingosine-1-phosphate receptor 1 antibody, sphingosine-1-phosphate receptor 1 L homeolog antibody, S1PR1 antibody, S1pr1 antibody, s1pr1 antibody, s1pr1.L antibody
Background
Sphingosine-1-phosphate receptor 1 (S1P receptor 1 or S1P1), also known as endothelial differentiation gene 1 (EDG1) is a protein that in humans is encoded by the S1PR1 gene. S1PR1 plays an important role in cell migration reorganizing the actin cytoskeleton and by the formation of lamellipodia in response to the activity of sphingosine kinase SPHK1. Diseases associated with S1PR1 include follicular thyroid carcinoma and multiple sclerosis. It is mainly expressed on endothelial cells, vascular smooth muscle cells (low), fibroblasts, melanocytes and cells of epithelioid origin.
Molecular Weight
40 kDa
Gene ID
1901
UniProt
P21453
Pathways
Signaling Events mediated by VEGFR1 and VEGFR2
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