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S1PR1 antibody (AA 1-320)

S1PR1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5027519
  • Target See all S1PR1 Antibodies
    S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))
    Binding Specificity
    • 15
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-320
    Reactivity
    • 88
    • 59
    • 45
    • 8
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 86
    • 8
    Rabbit
    Clonality
    • 76
    • 18
    Polyclonal
    Conjugate
    • 52
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This S1PR1 antibody is un-conjugated
    Application
    • 71
    • 38
    • 15
    • 15
    • 14
    • 13
    • 12
    • 8
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Protein A Chromatography
    Immunogen
    A partial length recombinant S1PR1 protein (amino acids 1-320) was used as the immunogen for this antibody.
    Isotype
    IgG
    Top Product
    Discover our top product S1PR1 Primary Antibody
  • Application Notes
    WB:4-6 μg/mL
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    PBS containing 0.05 % BSA, PH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • Target
    S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))
    Alternative Name
    S1PR1 (S1PR1 Products)
    Synonyms
    CD363 antibody, CHEDG1 antibody, D1S3362 antibody, ECGF1 antibody, EDG-1 antibody, EDG1 antibody, S1P1 antibody, AI849002 antibody, Edg1 antibody, Lpb1 antibody, S1p antibody, S1p1 antibody, S1P receptor 1 antibody, S1P receptor Edg-1 antibody, edg1 antibody, etID43307.22 antibody, s1p1 antibody, wu:fb98f05 antibody, s1pr1 antibody, xts1p1 antibody, sphingosine-1-phosphate receptor 1 antibody, sphingosine-1-phosphate receptor 1 L homeolog antibody, S1PR1 antibody, S1pr1 antibody, s1pr1 antibody, s1pr1.L antibody
    Background
    Sphingosine-1-phosphate receptor 1 (S1P receptor 1 or S1P1), also known as endothelial differentiation gene 1 (EDG1) is a protein that in humans is encoded by the S1PR1 gene. S1PR1 plays an important role in cell migration reorganizing the actin cytoskeleton and by the formation of lamellipodia in response to the activity of sphingosine kinase SPHK1. Diseases associated with S1PR1 include follicular thyroid carcinoma and multiple sclerosis. It is mainly expressed on endothelial cells, vascular smooth muscle cells (low), fibroblasts, melanocytes and cells of epithelioid origin.
    Molecular Weight
    40 kDa
    Gene ID
    1901
    UniProt
    P21453
    Pathways
    Signaling Events mediated by VEGFR1 and VEGFR2
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