TOX3 antibody (AA 232-442)

Catalog No. ABIN5027585

The Mouse Monoclonal anti-TOX3 antibody (Clone ABM44A1) (ABIN5027585) specifically detects TOX3 in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for TOX3 antibody (AA 232-442) (ABIN5027585)

Target: TOX3 (TOX High Mobility Group Box Family Member 3 (TOX3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TOX3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: ABM44A1

Product Details anti-TOX3 Antibody

Binding Specificity: AA 232-442

Purification: Protein G Chromatography

Immunogen: A partial length recombinant TOX-3 protein (amino acids 232-442) was used as the immunogen for this antibody

Isotype: IgG1 kappa

Application Details

Application Notes: WB: 2-4 μg/mL, IHC: 5 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for TOX3

Target: TOX3 (TOX High Mobility Group Box Family Member 3 (TOX3))

Alternative Name: TOX-3

Background: TOX high mobility group box family member 3 (TOX-3) is a member of a subfamily of transcription factors that contains a High Mobility Group box (HMG-box), involved in bending and unwinding of DNA and alteration of chromatin structure. It has two transcript variants encoding different isoforms.TOX3 is expressed in estrogen receptor-positive mammary epithelial cells, including progenitor cells and highly expressed in luminal B breast cancers. Its over expression in human oligodendrocytes reduced cellular death under conditions mimicking Spinal cord injury (SCI).

Molecular Weight: 63 kDa

Gene ID: 27324

UniProt: O15405

Pathways: Chromatin Binding