GLUT1 antibody (Internal Region)

Catalog No. ABIN504732

The Rabbit Polyclonal anti-GLUT1 antibody (ABIN504732) specifically detects GLUT1 in WB, IHC, IF and ICC. The antibody is reactive with Human, Rat, Mouse, Rabbit, Cow and Protozoa samples.

Quick Overview for GLUT1 antibody (Internal Region) (ABIN504732)

Target: GLUT1 (SLC2A1) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1))

Reactivity: Human, Rat, Mouse, Rabbit, Cow, Protozoa

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLUT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-GLUT1 Antibody

Binding Specificity: AA 300-400, Internal Region

Cross-Reactivity: Cow (Bovine), Human, Mouse (Murine), Primate, Rabbit, Rat (Rattus)

Purification: affinity purified

Immunogen: A synthetic peptide to an internal region (within AA 300-400) of the human LPIN1 protein. [Swiss-Prot# Q14693].

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: -20 °C

Target Details for GLUT1

Target: GLUT1 (SLC2A1) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1))

Alternative Name: GLUT1

Background: Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are seven types of glucose transport carrier proteins, designated as Glut 1 to 7. Molecular cloning of glucose transporters have identified a family of closely related genes that encodes at least 7 proteins exhibiting high degree of amino acid homology (45% to 65%), all in the molecular weight range of 40 to 60 kDa. Some transporters exhibit dynamic trafficking between intracellular storage sites and plasma membranes in response to various stimuli. In some tissues Glut proteins are asymmetrically distributed between apical and basolateral membranes, as in blood brain barrier and blood testis barriers. GLUT1 is a major glucose transporter in the mammalian blood brain barrier. It is ubiquitous, and is present at high levels in primate erythrocytes and brain endothelial cells.

UniProt: Q14693

Pathways: Sensory Perception of Sound, Dicarboxylic Acid Transport, Warburg Effect